Certain key things are known about what causes Rett, which is a huge advantage in terms of trying to find treatments and a cure. We know that: It is a single gene disorder. It has been widely demonstrated to be reversible when the missing protein is replaced
Rett Syndrome is caused by a lack of MeCP2 protein. Putting the protein back in mice, reverses symptoms. In 2007, Adrian Bird's lab demonstrated that the symptoms of Rett Syndrome could be successfully reversed in mice when protein levels were restored. Putting the protein back in
There are several different approaches in terms of research: putting the protein back: this approach aims to recreate the successful reversal experiments on mice, from 2007, which showed that putting the MeCP2 protein back reverses the symptoms of Rett. improving symptoms: many of the symptoms of Rett could